Use of specific binding molecules in potentiating igf-i...

Details Use of specific binding molecules in potentiating igf-i... Use of specific binding molecules in potentiating igf-i...

C - Chemistry, Metallurgy

07

K

C07K 16/26 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/30 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/65 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2141861

2141861 9404569 PCTABS00030 Antibodies and other specific binding molecules which bind to insulin-like growth factor-I (IGF-I), particularly the 1-17, 18-21, 22-37, 45-53, 54-60, 59-70 or, especially, the 36-44 region, potentiate or enhance its activity. The antibodies may be generated in situ by administering an appropriately antigenic molecule. IGF-I potentiation is useful in a wide range of clinical conditions.

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