C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/14 (2006.01) C07D 257/04 (2006.01) C07D 417/04 (2006.01) C07F 9/11 (2006.01) C07F 9/12 (2006.01) C07F 9/547 (2006.01) G01N 31/22 (2006.01) G01N 33/52 (2006.01)
Patent
CA 2084036
This invention relates to sulfonate and phosphonate salts of tetrazolium compounds wherein the anion X.theta.is represented by the formula: (see formula I) wherein R is an organic radical suitable for increasing the solubility of the tetrazolium salt in an aqueous or polar non-aqueous solvent, and the tetrazolium salt is represented by the formula: (see formula II) wherein X.theta. is the anion, R1 and R2 are phenyl groups and R3 is phenyl or 2-thiazolyl wherein the phenyl groups are unsubstituted or substituted as represented by the formula: (see formula III) wherein the Y groups, which can be the same or different, are alkoxy, aryloxy, alkyl, amido, alkylamido; arylamido, alkylthio, arylthio, halo, hydrogen, hydroxy, carbamoyl, carbalkoxy; carboxyl, cyano, nitro, sulfo, sulfonamido; sulfanoyl, trialkylamino or ureido. These salts possess enhanced solubility in various solvents which renders them particularly suitable for use as redox indicators in dry reagent, diagnostic test systems.
Blatt Joel M.
Hatch Robert P.
Corporation Bayer
Miles Inc.
Osler Hoskin & Harcourt Llp
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