Use of statins to inhibit formation of osteoclasts

Details Use of statins to inhibit formation of osteoclasts Use of statins to inhibit formation of osteoclasts

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 31/22 (2006.01) A61K 31/365 (2006.01) A61K 31/366 (2006.01) A61K 31/404 (2006.01) A61K 31/4418 (2006.01) A61K 31/47 (2006.01) A61K 31/505 (2006.01) A61P 19/10 (2006.01)

Patent

CA 2401319

A method for inhibiting the formation of osteoclasts comprising administering a therapeutically effective amount of a statin to a mammal in need thereof as well as pharmaceutical compositions, kits for containing such compositions comprising a statin or a method of treating or preventing a disease state selected from the group consisting of osteoporosis, Paget's disease, osteolysis, hypercalcemia of malignancy, osteogenesis imperfecta, osteoarthritis, alveolar bone loss, side effects of immunosuppressive therapy, and side effects of chronic glucocorticoid use by inhibiting the formation of osteoclasts comprising administering a therapeutically effective amount of a statin to a mammal in need thereof.

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