Use of steroidal alkaloid derivatives as inhibitors of...

Details Use of steroidal alkaloid derivatives as inhibitors of... Use of steroidal alkaloid derivatives as inhibitors of...

A - Human Necessities

61

K

A61K 31/585 (2006.01) A61K 31/00 (2006.01) A61K 31/4355 (2006.01) A61K 31/58 (2006.01)

Patent

CA 2326654

The present invention makes available assays and reagents inhibiting paracrine and/or autocrine signals produced by a hedgehog protein or aberrant activation of a hedgehog signal transduction pathway, e.g., which involve the use of a steroidal alkaloid or other small molecule.

L'invention concerne des dosages et des réactifs disponibles inhibant les signaux de paracrine et/ou d'autocrine produits par une protéine "hedgehog" ou une activation anormale d'une voie de transduction du signal, qui nécessite l'utilisation d'un alcaloïde stéroïde ou autre petite molécule.

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