Use of steroidal compounds as anti-fungal agents

A - Human Necessities – 61 – K

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A61K 31/575 (2006.01)

Patent

CA 2053902

2053902 9013298 PCTABS00002 Compounds of general formula (2), wherein X is a hydrogen atom or a hydroxyl group, Y is a hydrogen atom or a hydroxyl group and R is an alkyl group of 1 to 4 carbon atoms, have anti-fungal activity, especially against organisms selected from Candida spp. and the athlete's foot organism Trichophyton mentagrophytes and the ringworm organism Microsporum audonii. Further, the compounds wherein X and R are hydrogen atoms and Y is a hydroxyl group (or its non-toxic salts) are useful against Microsporum audonii.

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