A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/275 (2006.01) A61P 1/16 (2006.01) A61P 43/00 (2006.01) C12N 7/08 (2006.01)
Patent
CA 2415399
The present invention relates to the use, in humans, of inactivated parapoxviruses for the prophylaxis and treatment of diseases which are accompanied by an increased deposition of collagen, with it being possible for both internal organs, such as the liver, and the skin and its appended structures, to be affected. The invention relates, in particular, to liver fibrosis and/or liver cirrhosis consequent upon virus hepatitis, or to ethanol-induced liver diseases and to cystic fibrosis.
La présente invention concerne l'utilisation humaine de virus parapox inactivés pour la prophylaxie et le traitement de maladies associées à un accroissement des dépôts de collagène, les organes touchés pouvant être aussi bien des organes internes, tel le foie, que la peau et ses annexes épidermiques. Sont concernées en particulier la fibrose hépatique ou la cirrhose du foie à la suite de l'hépatite virale ou les maladies du foie induites par l'éthanol ainsi que la fibrose kystique.
Hirth-Dietrich Claudia
Knorr Andreas
Schlapp Tobias
Siegling Angela
Theiss Gudrun
Aicuris Gmbh & Co. Kg
Aktiengesellschaft Bayer
Fetherstonhaugh & Co.
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