Use of substituted 1,2,4-oxadiazole derivatives for...

C - Chemistry – Metallurgy – 07 – D

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C07D 271/06 (2006.01) A01N 43/82 (2006.01) A61K 31/41 (2006.01) A61K 31/42 (2006.01) A61K 31/44 (2006.01) C07D 413/00 (2006.01)

Patent

CA 2106897

The present invention relates to the use of substituted 1,2,4-oxadiazole derivatives of the general formula I (see formula I) in which R1 represents hydrogen, alkyl which is optionally substituted by halogen, alkoxy, hydroxyl, amino, alkylamino, dialkylamino, cycloalkylamino as well as cycloalkyl, optionally substituted aryl or hetaryl, R2 represents hydrogen and alkyl, X represents O, S, SO, SO2 and N-R3, R3 represents hydrogen, alkyl, alkylcarbonyl or halogenoalkylcarbonyl R4 represents identical or different radicals from the series comprising hydrogen, halogen, cyano, nitro, isothiocyanato, amino, aminoacyl, alkylamino, dialkylamino, trialkylammonium halide, sulphonylamino, hydroxyl, mercapto, alkyl, aralkyl, halogenoalkyl, alkoxy, aralkoxy, halogenoalkoxy, aryl, aryloxy, arylthio, arylsulphinyl, arylsulphonyl, alkylthio, halogenoalkylthio, alkylsulphinyl, halogeno-alkylsulphinyl, alkylsulphonyl, halogenoalkyl-sulphonyl, alkoxycarbonyl, alkylcarbonyl, alkylcarbonyloxy, alkoxyalkyl, alkoxyalkoxy, hydroxyalkoxy, hetarylmethyleneoxy, for combating endoparasites in medicine and veterinary medicine, and new compounds of the formula (I) and their preparation.

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