Use of substituted 2-mercaptonicotinic acid derivatives for...

C - Chemistry – Metallurgy – 07 – D

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C07D 213/82 (2006.01) A01N 43/40 (2006.01) A61K 31/44 (2006.01) A61K 31/535 (2006.01) C07D 213/80 (2006.01) C07D 213/84 (2006.01) C07D 401/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2052894

Use of substituted 2-mercaptonicotinic acid derivatives for combating endoparasites, new substituted 2-mercaptonicotinic acid derivatives and processes for their preparation Abstract The present invention relates to the use of compounds of the general formula I Image I in which R1 represents C1-C8-alkyl, aralkyl, aryl or hetero- aryl radicals which are optionally substituted by halogen, cyano, nitro, amino, alkylamino, amino- acyl, alkyl, aralkyl, halogenoalkyl, alkoxy, aryloxy, halogenoalkoxy, alkylthio, arylthio, alkylsulphinyl, arylsulphinyl, arylsulphonyl, halogenoalkylthio, haloganoalkylsulphinyl, halogenoalkylsulphonyl or carbonylaryl, X represents O, or / N-R3, R2 represents C1-5-alkyl, aralkyl, alkenyl or alkinyl, R3 represents H or alkyl or R1 and R3, together with the adjacent N atom, represent a 5 or 6-membered heterocycle which can contain O or N as addi- tional heteroatoms and is optionally substituted by C1-4-alkyl, Le A 27 948- R4 represents hydrogen, halogen, alkyl, halogeno- alkyl, cyano, nitro, amino, aminoacyl, phenyl, alkoxy, aryloxy, thioalkyl and arylthio which are optionally substituted, for combating endoparasites in medicine and veterin- ary medicine. Le A 27 9413

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