Use of substituted .beta.-hydroxyethylamines as potent...

A - Human Necessities – 61 – K

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A61K 31/355 (2006.01) A61K 31/13 (2006.01) A61K 31/135 (2006.01) A61K 31/165 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2043216

-1- HOE 90/F 164 ABSTRACT OF THE DISCLOSURE Use of substituted .beta.-hydroxyethylamines as potent inhibitors of the exoenzymes of fungi Compounds of the formula III Image III, which are already known as .beta.-blockers, are used for the prevention of fungal diseases and for the treatment of fungal diseases. A in these compounds is alk(en)yl or Image X is oxygen or sulfur, R(1) in these compounds is alk(en)yl or benzyl, R(2) and R(3) are (cyclo)alk(en)yl, (di)phenyl(alk)- (en)yl or together are a -(CH2)m- chain, and R(4), R(5) and R(6) can be a multiplicity of substituents customary in .beta.-blockers of this type.

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