Use of substrates as pharmacological chaperones

Details Use of substrates as pharmacological chaperones Use of substrates as pharmacological chaperones

C - Chemistry, Metallurgy

12

N

C12N 9/96 (2006.01) A61K 31/70 (2006.01) A61K 31/7032 (2006.01) A61K 31/726 (2006.01) A61K 31/727 (2006.01) A61K 31/737 (2006.01) A61K 38/00 (2006.01) C12N 9/10 (2006.01) C12N 9/14 (2006.01) C12N 9/16 (2006.01) C12N 9/24 (2006.01) C12N 9/80 (2006.01)

Patent

CA 2684042

Provided is a method of enhancing the activity of lysosomal enzymes using substrates that are derivatives of natural substrates as pharmacological chaperones.

L'invention concerne un procédé permettant d'augmenter l'activité d'enzymes lysosomiales à l'aide de substrats qui sont des dérivés de substrats naturels comme chaperons pharmacologiques.

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