Use of succinate as a diagnostic tool

Details Use of succinate as a diagnostic tool Use of succinate as a diagnostic tool

C - Chemistry, Metallurgy

12

Q

C12Q 1/00 (2006.01) G01N 33/50 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2321833

A method and kit for detecting a disease state, characterized by a localized hypoxic/ischemic cell population or other cells with altered metabolisms similar to hypoxic/ischemic cells, in an animal are described. The method comprising the step of determining the concentration of succinate in a bodily fluid sample of said animal.

L'invention concerne un procédé et une trousse pour détecter chez un animal, un état morbide caractérisé par une population cellulaire hypoxique/ischémique localisée ou d'autres cellules à métabolisme modifié similaires aux cellules hypoxiques/ischémiques. Le procédé consiste à évaluer la concentration de succinate dans un échantillon de fluide biologique dudit animal.

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