Use of sulodexide for the treatment of diabetic nephropathy

Details Use of sulodexide for the treatment of diabetic nephropathy Use of sulodexide for the treatment of diabetic nephropathy

A - Human Necessities

61

K

A61K 31/737 (2006.01) A61K 9/48 (2006.01) A61K 31/726 (2006.01) A61P 13/12 (2006.01)

Patent

CA 2411243

The present invention provides oral formulations of Sulodexide for the treatment of diabetic nephropathy in patients with both insulin dependent and non-insulin dependent diabetes mellitus. Oral formulations containing doses adapted for administration to obtain a reduction in albumin excretion in patients with both micro and macro albuminuria and to produce lasting improvement in albumin excretion rate are provided. Methods of treating diabetic nephropathy using these formulations are also provided.

L'invention concerne des formulations orales de Sulodexide destinées au traitement de la néphropathie diabétique chez les patients souffrant du diabète insulino-dépendant ou non insulino-dépendant; elle concerne des formulations orales contenant des doses conçues pour l'administration visant à réduire l'excrétion d'albumine chez les patients atteints de micro- et macro-albuminurie et à provoquer une amélioration durable en matière de vitesse d'excrétion d'albumine. L'invention concerne aussi des procédés pour traiter la néphropathie diabétique au moyen de ces formulations.

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