Use of superoxide dismutase mimetics and reductase...

A - Human Necessities – 61 – K

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Details

A61K 31/675 (2006.01) A61K 31/00 (2006.01) A61K 31/337 (2006.01) A61K 31/513 (2006.01) A61K 31/555 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2548108

The invention relates to the use of superoxide dismutase mimetics and reductase glutathione (preferably Mangafodipir) in order to produce an anticancer drug. Said mimetic, in particular makes it possible to potentiate the actions of antitumoral agents generating active oxygen forms on tumoral cells and to protect non-tumoral cells against said actions.

L'invention est relative à l'utilisation d'un mimétique de superoxyde dismutase et de glutathion réductase, de préférence le Mangafodipir, pour l'obtention d'un médicament anti-cancéreux. Ledit mimétique permet notamment de potentialiser les effets d'agents antitumoraux générateurs de formes réactives de l'oxygène sur les cellules tumorales, et de protéger les cellules non-tumorales contre ces effets.

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