Use of synthetic peptides to induce tolerance to pathogenic...

Details Use of synthetic peptides to induce tolerance to pathogenic... Use of synthetic peptides to induce tolerance to pathogenic...

A - Human Necessities

61

K

A61K 39/00 (2006.01) C07K 14/16 (2006.01) C07K 14/47 (2006.01) C07K 14/62 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2129351

2129351 9315750 PCTABS00024 The present invention relates, in general, to the use of synthetic peptides to induce tolerance to immunogenic peptides. In particular, the present invention relates to a method of inducing tolerance in a mammal to an immunogenic peptide or protein comprising administering to a mammal a synthetic toleragen comprising a hydrophobic peptide linked to the N-terminus or C-terminus of the immunogenic peptide or protein, under conditions such that the tolerance is induced.

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