Use of synthetic sulfated saccharides to enhance wound healing

Details Use of synthetic sulfated saccharides to enhance wound healing Use of synthetic sulfated saccharides to enhance wound healing

A - Human Necessities

61

K

167/199

A61K 31/70 (2006.01) C07H 11/00 (2006.01)

Patent

CA 1292185

USE OF SYNTHETIC SULFATED SACCHARIDES TO ENHANCE WOUND HEALING Abstract of the Disclosure The use of sulfated oligosaccharides, particularly mono- and disaccharides, and their salts to enhance healing of wounds is described. Preferred saccharides are those having three or more sulfate groups, with persulfation being most preferred. Preferred salts are the soluble salts most preferably the alkali metal salts, particularly potassium and sodium salts. Sucrose octosulfate is the most preferred material. The saccharides may be used in any form, includ- ing liquids, gels or time release polymers. In preferred practice the saccharide is used in combination with colla- gen. Wounds, in particular those ocurring in the skin and bone tissues, may be treated with the compositions. Wound healing is promoted even in wounds, such as decubitis ulcers, which are commonly resistent to the natural healing process.

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