Use of tam receptor inhibitors as immunoenhancers and tam...

Details Use of tam receptor inhibitors as immunoenhancers and tam... Use of tam receptor inhibitors as immunoenhancers and tam...

A - Human Necessities

61

K

A61K 31/519 (2006.01) A61K 39/395 (2006.01) A61P 31/00 (2006.01) A61P 37/04 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2703519

This disclosure concerns compositions and methods for immunoenhancement and/or immunosuppression. In certain embodiments, the disclosure concerns methods of using a TAM receptor inhibitor for immunoenhancement, for example as a vaccine adjuvant, for the treatment of sepsis, or for treating an immunocompromised subject. Also disclosed are methods of screening for immunoenhancing agents. In other embodiments, the disclosure concerns methods of using a TAM receptor agonist for immunosuppression, for example as a treatment for an autoimmune disorder, for the treatment of an allergy, or for treating graft-versus-host disease in a subject. Also disclosed are methods of screening for immunosuppressive agents.

L'invention concerne des compositions et des méthodes d'immunostimulation et/ou d'immunosuppression. Dans certains modes de réalisation, l'invention concerne des méthodes d'utilisation d'un inhibiteur des récepteurs TAM pour l'immunostimulation, par exemple en tant qu'adjuvant vaccinal, pour le traitement du sepsis, ou pour le traitement d'un sujet immunodéprimé. L'invention concerne également des méthodes de criblage d'agents immunostimulants. Dans d'autres modes de réalisation, l'invention concerne des méthodes d'utilisation d'un agoniste des récepteurs TAM pour l'immunosuppression, par exemple en tant que traitement d'un trouble auto-immunitaire, pour le traitement d'une allergie, ou pour le traitement d'une maladie du greffon contre l'hôte chez un sujet. L'invention concerne enfin des méthodes de criblage d'agents immunosuppresseurs.

Affiliated with

Also associated with

Rating

Use of tam receptor inhibitors as immunoenhancers and tam... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of tam receptor inhibitors as immunoenhancers and tam..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of tam receptor inhibitors as immunoenhancers and tam... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1592119