Use of tgf-.beta.1 inhibitor peptides in the preparation of...

A - Human Necessities – 61 – K

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A61K 38/18 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2627298

The invention relates to a TGF-.beta.1 inhibitor peptide which is selected from among: peptide p144 having a sequence that corresponds to SEQ ID NO: 1, peptide p17 having a sequence that corresponds to SEQ ID NO: 2, a peptide that has at least 90 % homology with said peptides, or fragments of same. The invention relates to the use of said peptide in the preparation of an immune response modulating agent.

La présente invention concerne l'utilisation d'un peptide inhibiteur du facteur TGF- ß1 sélectionné parmi le peptide p144 dont la séquence correspond à SEQ ID NO:1, le peptide p17 dont la séquence correspond à SEQ ID NO:2, un peptide qui présente une homologie d'au moins 90 % avec ces peptides, ou des fragments de ces peptides, dans la préparation d'un agent modulateur de la réponse immunitaire.

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