C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/87 (2006.01) A61K 38/16 (2006.01) A61K 48/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01)
Patent
CA 2358040
The present invention relates to a nuclear transport agent, to a gene transfer system comprising said nuclear transport agent, to a method for transporting DNA into the nucleus of eukaryotic cells using said nuclear transport agent and to the use of said nuclear transport agent in gene therapy for treating cancer, viral infections, diseases of the nervous system, graft rejection and monogenic or polygenic hereditary diseases.
L'invention concerne un agent de transport nucléaire, un système de transfert de gène comprenant l'agent de transport nucléaire, un procédé pour transporter de l'ADN dans le noyau de cellules eucaryotes, à l'aide de l'agent de transport nucléaire, ainsi que l'utilisation dudit agent de transport nucléaire en thérapie génique pour traiter des cancers, des infections virales, des affections du système nerveux, des rejets de greffes, ainsi que des maladies héréditaires monogéniques ou polygéniques.
Christine Rainer
Siebenkotten Gregor
Amaxa Gmbh
Lonza Cologne Gmbh
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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