G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2518761
The invention relates to a method for the identification of active compounds for weight gain or loss or diabetes in a human or animal subject, characterised in that the effect of said compound is measured by (a) expression of at least one of the genes LEPROTL1 and OB- RGRP or a part thereof and/or (b) the intracellular transport up to the cellular membrane and/or (c) presence at the cellular membrane and/or (d) internalisation from the membrane of proteins coded by at least one of said genes or a part thereof.
La présente invention concerne une méthode d'identification de composés actifs sur la perte ou la prise de poids ou le diabète chez un sujet humain ou animal, caractérisé en ce que l'on mesure l'effet dudit composé sur (a) l'expression de l'un au moins des gènes LEPROTL1 et OB~ RGRP ou partie de ceux- ci, et/ou (b) le transport intracellulaire jusqu'à la membrane cellulaire, et/ou (c) la présence au niveau de la membrane cellulaire, et/ou (d) l'internalisation depuis la membrane, des protéines codées par l'un au moins desdits gènes ou partie de ceux-ci.
Bailleul Bernard
Belouzard Sandrine
Rouille Yves
Seron Karin
Centre National de La Recherche Scientifique - Cnrs
Gowling Lafleur Henderson Llp
LandOfFree
Use of the genes leprotl1 and ob-rgrp for the screening of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of the genes leprotl1 and ob-rgrp for the screening of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of the genes leprotl1 and ob-rgrp for the screening of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1416917