Use of the krit1 gene in angiogenesis

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A61P 43/00 (2006.01) C07K 14/515 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2377795

The invention concerns a method for diagnosing cavernous angiomas for detecting mutations in the <i>Krit1</i> gene. More particularly, said detection is performed by using nucleotide sequences. The invention further concerns the use of the <i>Krit1</i> gene for therapeutic purposes in the field of angiogenesis.

La présente invention a pour objet une méthode de diagnostic des cavernomes pour la détection de mutations dans le gène <i>Krit1</i>. En particulier, cette détection est mise en oeuvre au moyen de séquences nucléotidiques également objet de la présente invention. Elle concerne également l'utilisation du gène <i>Krit1</i> à des fins thérapeutiques dans le domaine de l'angiogenèse.

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