Use of thermochromic liquid crystals in reflectometry based...

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G01N 33/52 (2006.01) C12Q 1/26 (2006.01) G01K 11/00 (2006.01) G01K 11/12 (2006.01) G01N 33/543 (2006.01) G01N 33/558 (2006.01) G01N 37/00 (2006.01)

Patent

CA 2218008

Disclosed is a method for improving the accuracy of temperature sensitive diagnostic assays which are carried out using reflectance spectrometers to detect color changes in a solid test system which has been contacted with a fluid test system suspected of containing an analyte whose presence and/or concentration is being sought. The improvement involves determining the temperature of the solid test material by measuring the reflectance of a thermochromic liquid crystal in close proximity to the solid test material and correcting the result of the assay for a change in temperature from a pre-selected nominal temperature.

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