Use of thiazolidinedione derivatives and related...

A - Human Necessities – 61 – K

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A61K 31/425 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2168751

Novel methods of using thiazolidinone derivatives and related antihyperglycemic agents to treat populations at risk for developing noninsulin-dependent diabetes mellitus (NIDDM) and complications arising therefrom are disclosed. In one embodiment, the compounds of the invention are used to treat polycystic ovary syndrome in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus. In another embodiment, the compounds of the invention are used to treat gestational diabetes in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus.

L'invention concerne un procédé utilisant des dérivés de thiazolidinédione et des agents anti-hyperglycémiants apparentés pour le traitement de populations risquant de développer un diabète sucré non insulinodépendant et les complications pouvant en découler. Dans une réalisation, les composés de l'invention sont utilisés pour le traitement du syndrome des ovaires polykystiques afin de prévenir ou de retarder l'installation du diabète sucré non insulinodépendant. Dans une autre réalisation, les composés sont utilisés pour le traitement des diabètes gestationnels afin de prévenir ou de retarder l'installation du diabète sucré non insulinodépendant.

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