Use of tinospora extract in the treatment of immune...

A - Human Necessities – 61 – K

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A61K 39/39 (2006.01)

Patent

CA 2432488

Immunomodulating pharmacologically and biologically active compositions containing a standardized extract of the plant Tinospora cordifolia, a process for their preparation and their use in dosage forms for healthcare, nutrition and treatment of disorders modulated by the immune system are described. The process includes preparation of an extract from plant parts of T. cordifolia and standardization of the extract by phagocytosis and LC-MS single ion recording assays. Methods of treating immunomodulatory deficiencies in healthcare are also disclosed using the compositions.

L'invention concerne des compositions immunomodulatrices pharmaceutiquement et biologiquement actives contenant un extrait standardisé de la plante <i>Tinospora cordifolia</i>, un procédé de fabrication de ces compositions, et leur utilisation dans des formes posologiques de soin, de nutrition, et de traitement de maladies modulées par le système immunitaire. Le procédé selon l'invention consiste à préparer un extrait de parties de la plante <i>T. </i><i>cordifolia </i> et à standardiser cet extrait par phagocytose et dosages d'enregistrement monoionique LC-MS (chromatographie liquide/spectrométrie de masse). L'invention concerne également des procédés de traitement de déficiences immunomodulatoires faisant intervenir lesdites compositions.

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