Use of topical treatment compositions comprising alpha...

Details Use of topical treatment compositions comprising alpha... Use of topical treatment compositions comprising alpha...

A - Human Necessities

61

K

A61K 31/19 (2006.01) A61K 8/365 (2006.01) A61P 17/02 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2190377

A method is provided to treat and or prevent striae distensae lesions by topically applying to the skin affected with the lesions an effective amount of a treatment composition containing an alpha hydroxy acid, such as glycolic acid, preferably by daily application in a pharmaceutically acceptable vehicle, such as a cream base, at a concentration of from 2 to 30 percent by weight. When applied during the striae rubrae stage, the alpha hydroxy acid may be effective to prevent the formation of striae albae lesions, and when applied in either stage, the alpha hydroxy acid may be effective to reduce the width and depth of the lesions, and improve the color of striae rubrae.

L'invention se rapporte à un procédé de traitement et/ou de prévention des lésions dues aux vergetures qui consiste à appliquer localement, sur la peau affectée par les lésions, une quantité efficace d'une composition de traitement contenant un acide hydroxy alpha, tel que l'acide glycolique, ce dernier étant appliqué de préférence quotidiennement, dans un excipient pharmaceutiquement acceptable, tel qu'une base sous forme de crème, dans une concentration comprise entre 2 et 30 pour cent en poids. Lorsqu'il est appliqué au stade des vergetures rouges, l'acide hydroxy alpha peut être efficace pour prévenir la formation des vergetures blanches, et lorsqu'il est appliqué à l'un ou l'autre stade, l'acide hydroxy alpha peut être efficace pour réduire la largeur et la profondeur des lésions, et atténuer la couleur des vergetures rouges.

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