Use of toremifene and its metabolites for the reversal of...

A - Human Necessities – 61 – K

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167/119, 167/180

A61K 31/135 (2006.01) A61K 33/24 (2006.01) A61K 31/71 (1990.01)

Patent

CA 2023630

A compound comprising toremifene or its metabolite N-demethyltoremifene or 4-hydroxytoremifene, or a non-toxic pharmaceutically acceptable salt thereof may be used for the reversal of multidrug resistance of cancer cells to cytotoxic drugs in the treatment of cancer with at least one cytotoxic drug.

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