Use of treprostinil to treat and prevent ischemic lesions

Details Use of treprostinil to treat and prevent ischemic lesions Use of treprostinil to treat and prevent ischemic lesions

A - Human Necessities

61

K

A61K 31/191 (2006.01) A61K 31/201 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2549724

The present invention describes novel methods for using Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of ischemic lesions, such as digital ulcers, in subjects with scleroderma (including systemic sclerosis), Buerger~s disease. Raynaud~s disease, Raynaud~s phenomenon and/or other conditions that cause such lesions. The invention also relates to kits for treatment and/or prevention of ischemic lesions, comprising an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof.

La présente invention concerne de nouvelles méthodes d'utilisation du tréprostinil ou de son dérivé, ou un sel acceptable d'un point de vue pharmaceutique de ceux-ci, dans le traitement et/ou la prévention des lésions ischémiques, par exemple les ulcères digitaux, chez des sujets atteints de sclérodermie (y compris de sclérose systémique), de la maladie de Buerger, la maladie de Raynaud, le phénomène de Raynaud et/ou d'autres états pathologiques provoquant lesdites lésions. L'invention concerne également des kits de traitement et/ou de prévention des lésions ischémiques, comprenant une quantité efficace de tréprostinil ou de son dérivé, ou un sel acceptable d'un point de vue pharmaceutique de ceux-ci.

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