Use of tryptanthrin compounds for immune potentiation

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61K 38/16 (2006.01) A61K 39/00 (2006.01) A61K 39/39 (2006.01) A61P 31/00 (2006.01) A61P 37/04 (2006.01) C07D 487/14 (2006.01)

Patent

CA 2513655

The invention provides immunostimulatory compositions and methods of administration thereof. Also provided are methods of administering a tryptanthrin compound in an effective amount to enhance the immune response of a subject to an antigen. Also provided are methods of administering an effective amount of a tryptanthrin to stimulate the immune response in a subject for the treatment of cancer. Further provided are methods of administering a tryptanthrin compounds as an immunotherapeutic in the treatment of infectious diseases.

La présente invention concerne des compositions immunostimulantes et leurs procédés d'administration. L'invention se rapporte également à des procédés permettant d'administrer un composé de tryptanthrine dans une quantité efficace afin d'améliorer la réponse immunitaire d'un sujet à un antigène. L'invention concerne aussi des procédés qui consistent à administrer une quantité efficace d'une tryptanthrine pour stimuler la réponse immunitaire d'un sujet lors d'un traitement anticancéreux. L'invention porte enfin sur des procédés d'administration de composés de tryptanthrine comme agents immunothérapeutiques dans le traitement de maladies infectieuses.

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