G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/50 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2558770
The invention relates to the use of substances that modulate or inhibit the expression or activity of TWEAK in neural cells, for the manufacture of a medicament for the treatment and/or prophylaxis of neurological and/or psychiatric conditions. The invention furthermore relates to the use of substances that modulate or inhibit the expression or activity of the TWEAK receptor, or that modulate or inhibit the intracellular signalling of the TWEAK receptor, for the same purpose. In addition, the invention encompasses a method for the identification of substances that modulate or inhibit the expression or activity of TWEAK.
L'invention porte: sur l'utilisation de substances modulant ou inhibant l'expression ou l'activité du TWEAK dans les cellules neurales en vue de la fabrication d'un médicament de traitement et/ou prophylaxie de troubles neurologiques et/ou psychiatriques; sur l'utilisation de substances modulant ou inhibant l'expression ou l'activité du récepteur du TWEAK ou modulant ou inhibant la signalisation intracellulaire du récepteur du TWEAK dans ces mêmes buts; et sur une méthode d'identification de substances modulant ou inhibant l'expression ou l'activité du TWEAK.
Rossner Moritz
Schneider Armin
Schwaninger Markus
Vogt Gerhard
Axaron Bioscience Ag
Goudreau Gage Dubuc
Sygnis Bioscience Gmbh & Co. Kg
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