A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/44 (2006.01) A61P 9/10 (2006.01) C12N 9/06 (2006.01)
Patent
CA 2697929
The invention relates to the use of an urate oxidase, preferably recombinant urate oxidase, for example Rasburicase, for producing a medicament for the treatment or prophylaxis of disorders or indirect sequelae of the heart caused by ischemic or reperfusion events, for example during and after cardiac surgery like CABG (coronary artery bypass graft), PCI (percutaneous coronary intervention), transplantation, post myocardial infarction and for the treatment or prophylaxis of coronary artery disease or heart failure, for example congestive heart failure.
L'invention concerne l'utilisation d'une urate-oxydase, de préférence une urate-oxydase recombinée, la rasburicase par exemple, dans la production d'un médicament destiné à la prévention ou au traitement de troubles ou de séquelles indirectes cardiaques causés par des événements ischémiques ou de reperfusion, par exemple pendant et après une intervention de chirurgie cardiaque telle qu'un pontage aortocoronarien, une intervention coronarienne percutanée (ICP), une transplantation, après un infarctus du myocarde et dans la prévention ou le traitement de la coronaropathie ou de l'insuffisance cardiaque, de l'insuffisance cardiaque congestive par exemple.
Linz Wolfgang
Schaefer Matthias
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis
LandOfFree
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