Use of vitamin d receptor agonists and precursors to treat...

Details Use of vitamin d receptor agonists and precursors to treat... Use of vitamin d receptor agonists and precursors to treat...

C - Chemistry, Metallurgy

12

Q

C12Q 1/02 (2006.01) A61K 31/59 (2006.01) A61P 19/04 (2006.01) C12Q 1/26 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2703994

This application relates to methods of treating, preventing, and ameliorating fibrosis, such as fibrosis of the liver, kidney, or pancreas. In particular, the application relates to methods of using a vitamin D receptor agonist (such as vitamin D, vitamin D analogs, vitamin D precursors, and vitamin D receptor agonists precursors) for the treatment of fibrosis. Also disclosed are methods for screening for agents that treat, prevent, and ameliorate fibrosis.

L'invention porte sur des procédés de traitement, de prévention et d'amélioration de la fibrose, telle que la fibrose du foie, du rein ou du pancréas. En particulier, l'invention porte sur des procédés d'utilisation d'un agoniste du récepteur de la vitamine D (tel que la vitamine D, les analogues de la vitamine D, les précurseurs de la vitamine D et les précurseurs des agonistes des récepteurs de la vitamine D) pour le traitement de la fibrose. L'invention porte également sur des procédés de criblage des agents qui traitent, préviennent et améliorent la fibrose.

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