Use of xanthine derivatives for the treatment of muscle...

Details Use of xanthine derivatives for the treatment of muscle... Use of xanthine derivatives for the treatment of muscle...

A - Human Necessities

61

K

A61K 31/52 (2006.01)

Patent

CA 2089959

HOE 92/F 049 Abstract of the disclosure The use of xanthine derivatives for the treatment of muscle damage after interruption of the blood circulation Xanthine derivatives of the formula I Image (I) where at least one of the radicals R1 and R3 is a radical of the formula Ia Image (Ia) R4 is a (C1-C3)-alkyl radical, n is an integer of 2 - 5 and - if only one of the radicals R1 and R3 is such a tertiary hydroxyalkyl group of the formula Ia - the other radical is a hydrogen atom or an aliphatic hydrocarbon radical R5 which has up to 6 carbon atoms and whose carbon chain can be interrupted by up to 2 oxygen atoms or can be substituted by an oxo group or up to two hydroxyl groups, where there oxo and hydroxyl groups are separated by at least 2 carbon atoms from the ring nitrogen, and R2 is an alkyl group with 1 - 4 carbon atoms, are suitable for the preparation of pharmaceuticals for the prophyl- axis and treatment of muscle damage which may occur after interruption of the blood circulation.

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