Use of xenon as neuroprotectant in a neonatal subject

A - Human Necessities – 61 – K

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A61K 33/00 (2006.01) A61K 31/08 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2576156

The present invention relates to the use of xenon in the preparation of a medicament for preventing and/or alleviating one or more anesthetic-induced neurological deficits in a neonatal subject. The present invention further relates to combinations of xenon and sevoflurane, and use thereof as preconditioning agents for administration prior to hypoxic-ischaemic injury.

La présente invention concerne l'utilisation de xénon dans la préparation d'un médicament servant à prévenir et/ou à réduire un ou plusieurs des déficits neurologiques induits par un anesthésiant chez un sujet néonatal. La présente invention concerne en plus des associations de xénon et de sévoflurane et l'utilisation de celles-ci comme agents de préconditionnement pour une administration avant une blessure hypoxique ischémique.

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