Use of xenon for treating neurointoxications

A - Human Necessities – 61 – K

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A61K 33/00 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2367136

The present invention relates to the use of xenon or xenon gas mixtures for treating neurointoxiations. In particular, the present invention is directed to such a xenon use in which the neurointoxiation is caused by a neurotransmitter excess. Xenon can reduce the release of neurotransmitters, particularly dopamine, which are caused e.g. by hypoxic situations such as an apoplexy or a craniocerebral trauma. A preparation containing xenon can also be used as therapeutic agent in the case of depressions, schizophrenia and Parkinson's disease, in which the neurotransmitter equilibrium is also disturbed. The application by inhalation is simple and the harmlessness of xenon has already been proved by its use as anesthetic agent.

L'invention porte sur l'utilisation de xénon ou de ses mélanges gazeux pour traiter les neurointoxications, et en particulier celles dues un excès de neurotransmetteurs. Le xénon peut freiner la libération des neurotransmetteurs et en particulier de la dopamine causée par exemple par des états hypoxiques tels que l'apoplexie ou les traumatismes craniocérébraux. On peut également utiliser une préparation à base de xénon comme agent thérapeutique en cas de dépression, de schizophrénie ou de maladie de Parkinson, où l'équilibre des neurotransmetteurs se trouve perturbé. L'application par inhalation est simple, et l'innocuité du xénon comme anesthésiant a déjà été prouvée.

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