C - Chemistry – Metallurgy – 08 – B
Patent
C - Chemistry, Metallurgy
08
B
C08B 37/00 (2006.01) A61K 31/715 (2006.01) A61K 31/74 (2006.01) A61K 38/00 (2006.01) A61K 38/16 (2006.01) A61P 37/02 (2006.01) C07H 5/06 (2006.01) G01N 33/48 (2006.01) G06F 19/00 (2006.01)
Patent
CA 2436666
The invention relates to three-dimensional molecular structure determination of polymers, three-dimensional computer molecular modeling, rational drug design, and immunomodulatory polymers. In particular the invention is directed to immunomodulatory polymers, as well as to methods for designing, selecting, and screening therapeutic agents having immunomodulatory activity. Furthermore, the invention relates toimmunomodulatory polysaccharides, including those bacterial origin such as B. fragilis capsular polysaccharide PS A2, and preparations thereof.
La présente invention concerne la détermination de la structure moléculaire tridimensionnelle de polymères, la modélisation moléculaire informatique tridimensionnelle, l'élaboration rationnelle de substances thérapeutiques et des polymères immunomodulateurs. De manière plus spécifique, cette invention se rapporte à des polymères immunomodulateurs ainsi qu'à des procédés d'élaboration, de sélection et de criblage d'agents thérapeutiques ayant une activité immunomodulatrice.
Kasper Dennis L.
Roehrl Michael H.
Wang Ying
Brigham And Women's Hospital Inc.
Smart & Biggar
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