Useful form of anhydrous paroxetine hydrochloride

Details Useful form of anhydrous paroxetine hydrochloride Useful form of anhydrous paroxetine hydrochloride

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2193939

Paroxetine hydrochloride anhydrous designated as Form IV having at least one, some or all of the following characteristics: a) Infrared spectra as shown in Schedules "A" and "B", b) A X-ray powder diffraction pattern as shown in Schedule "C", c) A melting point of between about 80°C to about 95°C, Schedule "C" - Form IV X-Ray Diffractogram (see fig. I)

Chlorhydrate de paroxétine anhydre, appelé Forme IV, possédant au moins une, plusieurs ou toutes les caractéristiques suivantes : a) spectres dans l'infra-rouge, selon les Annexes A et B; b) diffraction des rayons X par la méthode des poudres Debye-Scherrer, selon l'Annexe C; c) point de fusion se situant approximativement dans une plage de 80 à 95 degrés C; diffractogramme aux rayons X pour la Forme IV selon l'Annexe C (voir fig. I)

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