C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/24 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07K 14/52 (2006.01) C07K 14/525 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C07K 16/46 (2006.01) C12N 5/16 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2396793
Methods of using one or more agonists or antagonists to modulate activity of the members of the TNF and TNFR families referred to as TALL-1, APRIL, TACI, and BCMA are provided. The methods include in vitro, in situ, and/or in vivo diagnosis and/or treatment of mammalian cells or pathological conditions associated with TALL-1, APRIL, TACI, or BCMA, using one or more agonist or antagonist molecules. The methods of treatment disclosed by the invention include methods of treating immune related diseases and cancer.
L'invention porte sur une méthode d'utilisation d'un ou plusieurs agonistes ou antagonistes pour moduler l'activité de membres des familles TNF et TNFR dits TALL-1, APRIL, TACI, et BCMA. Ladite méthode consiste en diagnostics in vitro, in situ, et/ou in vivo et/ou en traitements de cellules de mammifère ou d'états pathologiques associés au TALL-1, au APRIL, au TACI, au BCMA, recourant à une ou plusieurs molécules agonistes ou antagonistes. Les méthodes de traitement de l'invention englobent le traitement de maladies liées à l'immunité, et du cancer.
Ashkenazi Avi J.
Dodge Kelly H.
Grewal Iqbal
Kim Kyung Jin
Marsters Scot A.
Genentech Inc.
Smart & Biggar
LandOfFree
Uses of agonists and antagonists to modulate activity of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Uses of agonists and antagonists to modulate activity of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Uses of agonists and antagonists to modulate activity of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1971219