Uses of bortezomib in predicting survival in multiple...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) G01N 33/15 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2748759

The present invention provides a method of predicting outcome of treatment for multiple myeloma based on determining certain cytogenetic anomalies and considering gene expression profiling risks. Also provided are statistical methods employed to define variables independently impacting outcomes. Further provided is method of treatment of myeloma patients.

La présente porte sur un procédé de prédiction de résultat d'un traitement pour un myélome multiple basé sur la détermination de certaines anomalies cytogénétiques et la considération de risques d'établissement de profil d'expression génique. L'invention porte également sur des procédés statistiques employés pour définir des variables affectant indépendamment les résultats. L'invention porte en outre sur un procédé de traitement de patients atteints de myélome.

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