A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/704 (2006.01) A61K 31/337 (2006.01) A61K 31/365 (2006.01) A61K 31/47 (2006.01) A61K 31/475 (2006.01) A61K 31/555 (2006.01) A61K 45/06 (2006.01) C12Q 1/02 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2382427
Combinations of diterpenoid triepoxides and anti-proliferative agents are used in a combination therapy to treat hyperproliferative disorders. Anti- proliferative agents of interest include agents active in killing tumor cells, as well as immunosuppressants, and a variety of other agents that reduce cellular proliferation in targeted tissues. Synergistic combinations provide for comparable or improved therapeutic effects, while lowering adverse side effects.
L'invention concerne l'utilisation de triépoxydes diterpénoïdes combinés à des agents anti-prolifératifs comme thérapie combinée de traitement des troubles hyperprolifératifs. Parmi les agents anti-prolifératifs utiles dans le cadre de l'invention figurent les agents induisant la destruction des cellules tumorales, les immunosuppresseurs, ainsi que divers autres agents réduisant la prolifération cellulaire dans des tissus cibles. Ces combinaisons synergiques, qui ont des effets thérapeutiques comparables ou supérieurs à ceux des autres médicaments, présentent des effets secondaires atténués.
Lennox Edwin S.
Musser John H.
Rosen Glenn D.
Fetherstonhaugh & Co.
Pharmagenesis
The Board Of Trustees Of The Leland Stanford Junior University
LandOfFree
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