Uses of ion channel modulating compounds

Details Uses of ion channel modulating compounds Uses of ion channel modulating compounds

A - Human Necessities

61

K

A61K 31/40 (2006.01)

Patent

CA 2524034

Methods, formulations, dosing regimes, and routes of administration for the treatment or prevention of arrhythmias, including the treatment or prevention of atrial fibrillation. In these methods, the disease or condition is treated or prevented by administering one or more ion channel modulating compounds to a subject, where the ion channel modulating compound or compounds produce specific plasma levels in the subject. The ion channel modulating compounds may be cycloalkylamine ether compounds, particularly cyclohexylamine ether compounds.

L'invention concerne des procédés, des préparations, des schémas posologiques et des voies d'administration pour le traitement ou la prévention d'arythmies, dont le traitement ou la prévention de la fibrillation auriculaire. Dans ces procédés, la maladie ou l'état est traité(e) ou empêché(e) par l'administration à un sujet d'un ou plusieurs composés modulant les canaux ioniques, le ou les composés de modulation de canaux ioniques produisant des taux de plasma spécifiques chez le sujet. Les composés modulant les canaux ioniques peuvent être des composés éther cycloamine, notamment des composés éther cyclohexylamine.

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