Uses of myostatin antagonists

Details Uses of myostatin antagonists Uses of myostatin antagonists

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 38/00 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 45/00 (2006.01)

Patent

CA 2632544

The present invention provides methods for treating disorders arising from hypogonadism, rheumatoid cachexia, cachexia due to burns, cachexia due to administration of chemical agents, cachexia due to diabetes, diabetic nephropathy, Prader Willi syndrome, excessive TNF-.alpha., and other muscle- related, metabolic and inflammatory disorders by administering myostatin antagonists to subjects suffering from such disorders.

L'invention concerne des méthodes de traitement de troubles liés à l'hypogonadisme, la cachexie rhumatoïde, la cachexie engendrée par des brûlures, la cachexie engendrée par l'administration d'agents chimiques, la cachexie engendrée par des diabètes, la néphropathie diabétique, le syndrome de Prader Willi, le TNF-.alpha. excessif et d'autres troubles relatifs aux muscles, métaboliques et inflammatoires. Les méthodes de traitement selon l'invention consistent à administrer des antagonistes de la myostatine à des sujets souffrant de tels troubles.

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