Using alkylmetal reagents for directed metalation of...

C - Chemistry – Metallurgy – 07 – F

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C07F 7/08 (2006.01) C07D 213/60 (2006.01) C07D 213/61 (2006.01) C07D 213/64 (2006.01) C07D 213/65 (2006.01) C07D 213/68 (2006.01)

Patent

CA 2521383

Substituted alkylmetal reagents such as (trimethylsilylmethyl)lithium are reacted with azaaromatic compounds and/or nitrogen heterocycle compounds to produce functionalized azaaromatic compounds and functionalized nitrogen heterocycle compounds.

On prend des réactifs alkylmétalliques substitués, tels que le (triméthyl-silyl-méthyl)lithium, et on les fait réagir sur des composés aza-aromatiques et/ou hétéroycliques azotés. On obtient ainsi des composés aza-aromatiques et des composés hétérocycliques azotés fonctionnalisés.

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