Using liquid crystals to detect affinity microcontact...

Details Using liquid crystals to detect affinity microcontact... Using liquid crystals to detect affinity microcontact...

G - Physics

01

N

G01N 33/53 (2006.01)

Patent

CA 2539436

The present invention provides methods, devices and kits for detecting a ligand. The methods involve capturing a ligand from a sample with an affinity substrate that includes a receptor for a ligand, transferring captured ligand to a detection surface and detecting the ligand on the detection surface with a liquid crystal. Accordingly, the capture step is decoupled from the detection step.

La présente invention concerne des méthodes, des dispositifs et des trousses destinés à la détection d'un ligand. Ces méthodes consistent à capturer un ligand à partir d'un échantillon avec un substrat d'affinité qui comporte un récepteur de ligand, à transférer le ligand capturé vers une surface de détection et à détecter le ligand situé sur ladite surface avec un cristal liquide. Par conséquent, l'étape de capture est découplée de l'étape de détection.

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