Using metal aquacomplexes for preparation pure amino acid...

C - Chemistry – Metallurgy – 07 – C

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C07C 227/44 (2006.01) A23L 1/304 (2006.01) A23L 1/305 (2006.01) A61K 31/198 (2006.01) A61K 33/24 (2006.01) C07B 43/04 (2006.01)

Patent

CA 2623964

A one-pot method for preparing water-soluble pure metal amino acid chelates in various chelate compositions using metal aquacomplexes is disclosed and described. The chelates obtained are free from other organic and inorganic additives including acids, salts, and ions and have high solubility and stability in aqueous solution. The pH of aqueous solutions of chelates is optimized for intestinal absorption by using different combinations of amino acids as ligands. The present invention establishes a process for providing a recommended level of intake of essential metals and essential amino acids by humans and animals by using chelates as nutritional supplements or pharmaceutical applications.

Dans l'invention, on divulgue et décrit une méthode permettant de préparer des chélates hydrosolubles purs composés d'acides aminés et de métaux de composition variable à l'aide d'hydrocomplexes métalliques dans un récipient unique. Les chélates obtenus ont exempts d'autres additifs organiques et inorganiques, y compris d'acides, de sels et d'ions, et présentent une très bonne solubilité et stabilité en solution aqueuse. Le pH des solutions aqueuses de chélates a été optimalisé pour une absorption intestinale maximale à l'aide de différentes combinations d'acides aminés en tant que ligands. La présente invention établit une méthode permettant de recommander la concentration des métaux essentiels et des acides aminés essentiels aux humains et aux animaux en utilisant les chélates dans les suppléments nutritionnels ou les compositions pharmaceutiques.

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