A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/381 (2006.01) A61K 31/136 (2006.01) A61K 31/235 (2006.01) A61K 31/4439 (2006.01) A61P 25/02 (2006.01) A61P 25/04 (2006.01) A61P 25/06 (2006.01) A61P 25/08 (2006.01) A61P 25/14 (2006.01) A61P 25/16 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) A61P 25/30 (2006.01) A61P 29/02 (2006.01)
Patent
CA 2537088
The present invention provides uses of compounds as medicaments for treating neurological disorders and chronic pain in mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.
L'invention concerne l'utilisation de composés comme médicaments pour le traitement des troubles neurologiques et de la douleur chronique chez un mammifère par administration d'une quantité efficace d'antagoniste sélectif vis-à-vis du courant sodique persistant, ayant pour ledit courant une sélectivité d'au moins un facteur 20 par rapport au courant sodique transitoire.
Adorante Joseph S.
Donello John E.
Ehring George R.
Malone Thomas
Wheeler Larry A.
Allergan Inc.
Gowling Lafleur Henderson Llp
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