Utilisation of dialkylfumarates for treating...

A - Human Necessities – 61 – K

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A61K 31/194 (2006.01) A61K 31/225 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2346438

The present invention relates to the use of certain dialkyl fumarates for the preparation of pharmaceutical preparations for use in transplantation medicine or for the therapy of autoimmune diseases and said compositions in the form of micro-tablets or pellets. For this purpose, the dialkyl fumarates may also be used in combination with conventional preparations used in transplantation medicine and immunosuppressive agents, especially cyclosporines.

L'invention concerne l'utilisation de dialkylfumarates déterminés pour la fabrication de préparations pharmaceutiques destinées à être utilisées en médecine de transplantation ou pour le traitement de maladies auto-immunes, ainsi que les préparations sous forme de micro-comprimés ou de granulés. Dans ce but, les dialkylfumarates peuvent être utilisés également en combinaison avec des préparations de types connus en médecine de transplantation et immunosuppressive, notamment avec des cyclosporines.

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