Utility of ret mutant in diagnosis and treatment of melanoma

Details Utility of ret mutant in diagnosis and treatment of melanoma Utility of ret mutant in diagnosis and treatment of melanoma

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 31/404 (2006.01) A61K 31/44 (2006.01) C12Q 1/02 (2006.01) A61K 31/713 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2705229

The invention relates to a method of detecting a RET mutant in a melanoma cell. Also disclosed is a method of modulating the activity of a RET mutant in a melanoma cell with an agent that interferes with the activity of the RET mutant.

Cette invention concerne un procédé de détection d'un mutant RET dans une cellule de mélanome. Elle décrit également un procédé de modulation de l'activité d'un mutant RET dans une cellule de mélanome par un agent qui interfère avec l'activité du mutant RET.

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