Vaccine

Details Vaccine Vaccine

C - Chemistry, Metallurgy

07

K

C07K 16/42 (2006.01) A61K 39/00 (2006.01) A61K 39/21 (2006.01) A61K 39/395 (2006.01) A61P 31/18 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2580319

The invention provides a method for generating anti-CD4 auto-antibodies comprising administering to an individual an anti-CD4 antibody molecule which has a low affinity for native CD4 in said individual or a protein or peptide comprising a CD4-like epitope, wherein administration of said antibody molecule, protein or peptide results in the generation of anti-CD4 auto- antibodies.

L'invention concerne un procédé permettant de produire des auto-anticorps anti-CD4, consistant à administrer à un individu une molécule d'anticorps anti-CD4 présentant une faible affinité par rapport à un CD4 natif chez ledit individu ou une protéine ou un peptide comprenant un épitope semblable à CD4, l'administration de cette molécule d'anticorps, de la protéine ou du peptide permettant de produire des auto-anticorps anti-CD4.

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