A - Human Necessities
61
K
A61K 39/09 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2690708
The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, an immunogenic composition for infants is provided comprising a multivalent Streptococcus pneumoniae vaccine comprising 2 or more capsular saccharide conjugates from different serotypes, wherein the composition comprises a serotype 22F saccharide conjugate. Such a vaccine may be used in infant populations to reduce the incidence of elderly pneumococcal disease such as exacerbations of COPD and/or IPD.
La présente invention trouve une application dans le domaine des vaccins pneumococciques conjugués à base de saccharides capsulaires. Plus particulièrement, elle concerne une composition immunogène pour nourrissons comprenant un vaccin multivalent contre Streptococcus pneumoniae renfermant au moins deux conjugués de saccharides capsulaires issus de différents sérotypes, cette composition renfermant un conjugué saccharidique du sérotype 22F. Ledit vaccin peut être administré à des populations de nourrissons en vue de réduire l'incidence d'une infection pneumococcique chez les personnes âgées, et notamment des exacerbations de la BPCO et/ou de l'infection pneumococcique invasive.
Biemans Ralph Leon
Hermand Philippe Vincent
Poolman Jan
Glaxosmithkline Biologicals S.a.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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