C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/24 (2006.01) A61K 39/00 (2006.01) C07K 14/47 (2006.01) C07K 14/54 (2006.01)
Patent
CA 2439628
The present invention relates to an isolated polypeptide useful for immunisation against self-antigens. In particular the invention relates to a self-protein that is capable of raising auto-antibodies when administered in vivo. The invention particularly relates to rendering human cytokines immunogenic in humans. The invention further relates to pharmaceutical compositions comprising such compounds and their use in medicine and to methods for their production.
L'invention concerne un polypeptide isolé utilisé dans l'immunisation contre des auto-antigènes. ElIe concerne plus précisément une auto-protéine pouvant augmenter le taux d'auto-anticorps lorsqu'elle administrée in vivo, ainsi que la possibilité de rendre les cytokines humains immunogènes chez les humains. Enfin, l'invention concerne des compositions pharmaceutiques contenant les composés susmentionnés ainsi que leur utilisation en médecine, et leurs méthodes de préparation.
Ashman Claire
Crowe James Scott
Ellis Jonathan Henry
Lewis Alan Peter
Glaxo Group Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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