A - Human Necessities
61
K
A61K 39/09 (2006.01) A61K 39/385 (2006.01)
Patent
CA 2634887
The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, an immunogenic composition for infants is provided comprising a multivalent Streptococcus pneumoniae vaccine comprising 2 or more capsular saccharide conjugates from different serotypes, wherein the composition comprises a serotype 22F saccharide conjugate. Such a vaccine may be used in infant populations to reduce the incidence of elderly pneumococcal disease such as exacerbations of COPD and/or IPD.
La présente invention concerne des vaccins pneumococciques à base de conjugués de saccharides capsulaires. Plus particulièrement, elle concerne une composition immunogène pour nourrissons comprenant un vaccin à Streptococcus pneumoniae multivalent renfermant au moins 2 conjugués de saccharides capsulaires issus de sérotypes différents, la composition comprenant un conjugué saccharidique de sérotype 22F. Ce vaccin peut être utilisé dans des populations de nourrissons en vue de réduire l'incidence d'une maladie pneumococcique chez les personnes âgées, et notamment les exacerbations de la BPCO et/ou de la maladie pneumococcique invasive.
Biemans Ralph Leon
Garcon Nathalie Marie-Josephe
Hermand Philippe Vincent
Poolman Jan
Van Mechelen Marcelle Paulette
Glaxosmithkline Biologicals Sa
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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